In some cases, ED can cause a strain on relationships and impact self-esteem. While each PDE5 inhibitor differs slightly, they’re very similar in treating erectile dysfunction. Shipping: Discreet, fast shipping is a must. Those with a history of blood pressure or heart issues, hormonal imbalances, mental health issues, and diabetes should consult their doctor before trying PDE5 inhibitors. However, all medications come with risks. It depends on the platform and insurance provider. You should also call your insurance company to see if they cover erectile dysfunction medications.Even if this drug is covered by Medicare or your insurance, we recommend you compare prices. The MDRx coupon or cash price may be less than your co-pay. Brand Brand . The cost for tadalafil oral tablet 5 mg is around $27 for a supply of 90 tablets, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the discount card which is accepted at most U.S. pharmacies. Tadalafil prices Oral Tablet. Tadalafil: 5 mg, 10 mg, or 20 mg, taken as needed; Cialis: mg, 5 mg, 10 mg, and 20 mg, taken as needed; The cost of the medication is from $ per month for Cialis and from $40 per month for.