Do not take a double dose to make up for a missed one. It can also interact with many medicines, particularly nitrates used in some types of heart disease and blood pressure medicines. You need to be sexually aroused for it to work. The starting dose we generally recommend is the 10mg pill. What special precautions should I follow? Subsequently, the FDA approved both vardenafil [27] and tadalafil in About tadalafil Brand names: Cialis, Adcirca. About tadalafil. Tadalafil is a medicine used to treat erection problems (erectile dysfunction) and symptoms of an enlarged prostate (benign prostate enlargement). It’s also sometimes used to treat pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs). CIALIS for Use as Needed. Creatinine clearance 30 to 50 mL/min: A starting dose of 5 mg not more than once per day is recommended, and the maximum dose is 10 mg not more than once in every 48 hours. Creatinine clearance less than 30 mL/min or on hemodialysis: The maximum dose is 5 mg not more than once in every 72 hours [see . Save £ Was £ 4 UNI | £ per 1UNI. Save 10 percent on Cialis Together 10mg Tablets Tadalafil 4 Tablets. Free next day delivery on selected medicines when you use code HEALTHFNDD, order by 8pm – online only. Helps you get and maintain an erection when you need it. Effective up to 36 hours.