Accuracy and References: We strive to provide accurate and up-to-date information in our content. Dosing Guidelines Typical Cialis dosages will differ depending on the conditions it’s prescribed to treat as well as other factors. An erection results from an increase in blood flow to the penis. Yes, but only from licensed and regulated pharmacies and with a valid prescription. Their pool of advisors ranges from renowned doctors, revered academics, and some of the most well-respected practitioners currently in the field of medicine. SesameCare has a team of qualified and professional medical experts who can design a personalized treatment plan that is fit for your goals.How Cialis Works. Tadalafil and other PDE5 inhibitors primarily work by inducing muscle relaxation. Tadalafil stops the breakdown of a chemical responsible for relaxing muscles. In ED and PAH, the drug targets muscle cells in blood vessels. When the blood vessel muscle cells relax, this expands the vessel and increases blood flow; this .  · But on average, its effects start to lessen 2 to 3 hours after you take a dose. The typical dose for once-daily Cialis for ED is milligrams (mg) to 5 mg. When used as needed for ED, the usual. Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include headache and indigestion. Tadalafil .